Khaled Taha, MD, MSc, MRCP, MRCEM; Tomás Breslin, MD, MRCP, FRCEM; John M. Moriarty, MD, FSIR; Shammy Ali, MBBS, MD; Bernhard Louw, MBChB, DipPEC (SA) – Paget-Schroetter Syndrome, or effort thrombosis, is a relatively rare disorder. It refers to axillary-subclavian vein thrombosis (ASVT) that is associated with strenuous and repetitive activity of the upper extremities [1]. Anatomical abnormalities at the thoracic outlet and repetitive trauma to the endothelium of the subclavian vein are key factors in its initiation and progression. Doppler ultrasonography is the preferred initial test, but contrast venography is the gold standard for diagnosis [1,2].